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Study identifier: NCT05359861 Synced from ClinicalTrials.gov · August 04, 2026
● Completed

Trial of Atezolizumab and Bevacizumab With SRF388 or Placebo in Patients With Hepatocellular Carcinoma

Condition: Hepatocellular Carcinoma  ·  Sponsor: Coherus Oncology, Inc.

PhasePhase 2
Planned participants30
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a Phase 2 trial composed of an open label Lead-In followed by a Randomized Phase designed to evaluate the efficacy and safety of SRF388 in combination with atezolizumab plus bevacizumab compared to placebo (inactive substance) in combination with atezolizumab plus bevacizumab in patients with first-line advanced or metastatic HCC.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (37)

University of Arizona Cancer Center - North CampusTucson, Arizona, United States
City of HopeDuarte, California, United States
University of Southern California - Norris Comprehensive Cancer CenterLos Angeles, California, United States
University of Florida Health Science Center - GainesvilleGainesville, Florida, United States
University of Miami, Sylvester Comprehensive Cancer CenterMiami, Florida, United States
Louisville VA Medical Center - Robley Rex VA Medical CenterLouisville, Kentucky, United States
Veterans Affairs Ann Arbor Healthcare SystemAnn Arbor, Michigan, United States
University of Michigan Health System (UMHS)Ann Arbor, Michigan, United States
Henry Ford HospitalDetroit, Michigan, United States
Veterans Affairs New York Harbor Healthcare System - Manhattan VA Medical CenterNew York, New York, United States
NYU Langone Medical Center - Laura and Isaac Perlmutter Cancer Center (NYU Cancer Institute (NYUCI))New York, New York, United States
University of Oklahoma Health Sciences Center - Stephenson Cancer CenterOklahoma City, Oklahoma, United States

+ 25 more locations — full list on the registry record.

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