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Study identifier: NCT05333874 Synced from ClinicalTrials.gov · August 05, 2026
● Active Not Recruiting

CIPHER Study: Pilot Study to Study the Role of ctDNA in Triple Negative and HER2 Positive Early Stage

Condition: Breast Cancer, Early-Onset  ·  Sponsor: Rutgers, The State University of New Jersey

PhaseEARLY_Phase 1
Planned participants34
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Primary Objective: 1\) To examine the impact of Circulating tumor DNA (ctDNA) (expressed as mean tumor molecules per ml) on treatment decision making in patients with early stage breast cancer after neoadjuvant therapy and surgery Secondary Objectives: 1. Understand ctNDA kinetics in the neoadjuvant and adjuvant setting 2. To identify any associations between clinical staging and measurable ctDNA

This description comes directly from the study's public registry record.

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Locations (12)

Trinitas Hospital and Comprehensive Cancer CenterElizabeth, New Jersey, United States
RWJBarnabas Health - Robert Wood Johnson University HospitalHamilton, New Jersey, United States
Jersey City Medical CenterJersey City, New Jersey, United States
Monmouth Medical Center - Southern CampusLakewood, New Jersey, United States
Cooperman Barnabas Medical CenterLivingston, New Jersey, United States
Monmouth Medical CenterLong Branch, New Jersey, United States
Robert Wood Johnson University HospitalNew Brunswick, New Jersey, United States
Rutgers Cancer Institute of New JerseyNew Brunswick, New Jersey, United States
Newark Beth Israel Medical CenterNewark, New Jersey, United States
Robert Wood Johnson Barnabas Hospital -SomersetSomerville, New Jersey, United States
Steeplechase Cancer CenterSomerville, New Jersey, United States
Monmouth Medical Center Vantage Point Infusion CenteWest Long Branch, New Jersey, United States

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