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Study identifier: NCT05333068 Synced from ClinicalTrials.gov · August 05, 2026
● Active Not Recruiting

COMBINE-INTERVENE: COMBINEd Ischemia and Vulnerable Plaque Percutaneous INTERVENtion to Reduce Cardiovascular Events

Condition: Multivessel Coronary Artery Disease · Ischemia · Vulnerable Plaque  ·  Sponsor: Diagram B.V.

PhaseNA
Planned participants1223
Who can joinAll sexes, 30 Years to 80 Years
Healthy volunteersNo

About this study

The COMBINE-INTERVENE Trial will investigate whether a PCI revascularization strategy based on combined FFR and OCT assessment is superior to a PCI revascularization strategy based on FFR-alone in patients with MVD with any presentation.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (49)

Monash MedicalClayton, Australia
Hamilton Health SciencesHamilton, Canada
McGill University Health CentreMontreal, Canada
Niagara Health System - St. Catherines SiteSaint Catharines, Canada
Aarhus University HospitalAarhus, Denmark
North-Estonia Medical CentreTallinn, Estonia
Centre Hospitalier Régional Universitaire de LilleLille, France
Clinique Louis PasteurNancy, France
Charité - Universitätsmedizin BerlinBerlin, Germany
Universitätsklinikum FrankfurtFrankfurt, Germany
Apex Heart InstituteAhmedabad, India
Apollo HospitalsBangalore, India

+ 37 more locations — full list on the registry record.

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