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Study identifier: NCT05298423 Synced from ClinicalTrials.gov · August 02, 2026
● Active Not Recruiting

Study of Pembrolizumab/Vibostolimab (MK-7684A) in Combination With Concurrent Chemoradiotherapy Followed by Pembrolizumab/Vibostolimab Versus Concurrent Chemoradiotherapy Followed by Durvalumab in Participants With Stage III Non-small Cell Lung Cancer (MK-7684A-006)

Condition: Carcinoma, Non-Small-Cell Lung  ·  Sponsor: Merck Sharp & Dohme LLC

PhasePhase 3
Planned participants611
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Researchers are looking for new ways to treat people with locally advanced non-small cell lung cancer (NSCLC). The goal of this study is to learn if people who receive the combination of vibostolimab and pembrolizumab (MK-7684A) live longer without the cancer getting worse and live longer overall than people who receive durvalumab.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (160)

VA Long Beach Healthcare System ( Site 2831)Long Beach, California, United States
VA West Los Angeles Medical Center ( Site 2808)Los Angeles, California, United States
Millennium Oncology Research Clinic ( Site 2801)Hollywood, Florida, United States
Mid Florida Hematology and Oncology Center ( Site 2800)Orange City, Florida, United States
Moffitt Cancer Center ( Site 2818)Tampa, Florida, United States
University of Chicago Medical Center ( Site 2828)Chicago, Illinois, United States
Franciscan St. Francis Health ( Site 2812)Indianapolis, Indiana, United States
MFSMC-HJWCI ( Site 2804)Baltimore, Maryland, United States
Boston Medical Center ( Site 2829)Boston, Massachusetts, United States
University of Massachusetts Chan Medical School ( Site 2815)Worcester, Massachusetts, United States
University of Missouri Hospital ( Site 2839)Columbia, Missouri, United States
Cox Medical Center North-Cox Medical Center/Hulston Cancer Center/ Radiation Oncology ( Site 2837)Springfield, Missouri, United States

+ 148 more locations — full list on the registry record.

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