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A Study to Evaluate the Efficacy and Safety of Giredestrant in Combination With Phesgo (Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf) Versus Phesgo in Participants With Locally Advanced or Metastatic Breast Cancer (heredERA Breast Cancer)
Condition: Locally Advanced or Metastatic Breast Cancer · Sponsor: Hoffmann-La Roche
About this study
This Phase III, randomized, two-arm, open-label, multicenter study will evaluate the efficacy and safety of giredestrant plus Phesgo compared with Phesgo after induction therapy with Phesgo plus taxane in participants with human epidermal growth factor receptor 2 (HER2)-positive, estrogen receptor (ER)-positive advanced breast cancer (metastatic or locally advanced disease not amenable to curative treatment) who have not previously received a systemic non-hormonal anti-cancer therapy in the advanced setting.
This description comes directly from the study's public registry record.
Talk to the study team
No contact information is available for this study as per the public registry record.
Always discuss trial participation with your own doctor first.
Locations (202)
| Arizona Clinical Research Center, Inc | Tucson, Arizona, United States | — |
| Los Angeles Hematology Oncology Medical Group | Los Angeles, California, United States | — |
| Cancer Specialists of North Florida | Jacksonville, Florida, United States | — |
| Maryland Oncology Hematology - Annapolis | Annapolis, Maryland, United States | — |
| Queens Hospital Cancer Center | Jamaica, New York, United States | — |
| Clinical Research Alliance | Westbury, New York, United States | — |
| West Cancer Center | Germantown, Tennessee, United States | — |
| CHRISTUS Spohn Cancer Center - Shoreline | Corpus Christi, Texas, United States | — |
| Texas Oncology - DFW | Dallas, Texas, United States | — |
| Texas Oncology - El Paso | El Paso, Texas, United States | — |
| Swedish Cancer Institute - Edmonds Campus | Edmonds, Washington, United States | — |
| Swedish Cancer Institute - Issaquah | Issaquah, Washington, United States | — |
+ 190 more locations — full list on the registry record.
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