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Study identifier: NCT05291091 Synced from ClinicalTrials.gov · August 02, 2026
● Active Not Recruiting

Phase 2 Study of EDG-5506 in Becker Muscular Dystrophy (GRAND CANYON)

Condition: Becker Muscular Dystrophy  ·  Sponsor: Edgewise Therapeutics, Inc.

PhasePhase 2
Planned participants244
Who can joinMale, 12 Years to 50 Years
Healthy volunteersNo

About this study

A study of sevasemten (EDG-5506) in Becker muscular dystrophy (known as CANYON) and pivotal cohort (known as GRAND CANYON). The EDG-5506-201 CANYON study was expanded to include an additional 120 adult participants in a cohort called GRAND CANYON, that is a multicenter, randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of sevasemten in adults with Becker. CANYON and GRAND CANYON are fully enrolled.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

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Locations (51)

Arkansas Children's HospitalLittle Rock, Arkansas, United States
UC San DiegoLa Jolla, California, United States
UCLA Medical CenterLos Angeles, California, United States
UC Irvine Medical CenterOrange, California, United States
Stanford Neuroscience Health CenterPalo Alto, California, United States
UC Davis Medical CenterSacramento, California, United States
UC DenverAurora, Colorado, United States
University of FloridaGainesville, Florida, United States
Rare Disease ResearchAtlanta, Georgia, United States
Northwestern UniversityChicago, Illinois, United States
Indiana University School of MedicineIndianapolis, Indiana, United States
University of IowaIowa City, Iowa, United States

+ 39 more locations — full list on the registry record.

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