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Study identifier: NCT05242484 Synced from ClinicalTrials.gov · August 02, 2026
● Active Not Recruiting

A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis

Condition: Colitis, Ulcerative  ·  Sponsor: Janssen Research & Development, LLC

PhasePhase 2
Planned participants577
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the efficacy and safety of JNJ-78934804 as compared to guselkumab and golimumab in participants with moderately to severely active ulcerative colitis who have had an inadequate initial response, loss of response, or intolerance to one or more approved advanced therapy.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

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Locations (403)

Valley Gastroenterology Medical GroupArcadia, California, United States
Southern California Research CenterCoronado, California, United States
Om Research LLCLancaster, California, United States
Cedars Sinai Medical CenterLos Angeles, California, United States
University of California San FranciscoSan Francisco, California, United States
University of ColoradoAurora, Colorado, United States
Peak Gastroenterology AssociatesColorado Springs, Colorado, United States
Medical Research Center of ConnecticutHamden, Connecticut, United States
Yale UniversityNew Haven, Connecticut, United States
MedStar Georgetown University HospitalWashington D.C., District of Columbia, United States
Pioneer Research Solutions Inc.Coconut Creek, Florida, United States
Digestive and Liver Disease InstituteKissimmee, Florida, United States

+ 391 more locations — full list on the registry record.

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