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Study identifier: NCT05238675 Synced from ClinicalTrials.gov · August 02, 2026
● Completed

A Study to Test Whether Different Doses of BI 1291583 Help People With Bronchiectasis

Condition: Bronchiectasis  ·  Sponsor: Boehringer Ingelheim

PhasePhase 2
Planned participants322
Who can joinAll sexes, 18 Years to 85 Years
Healthy volunteersNo

About this study

This study is open to adults with bronchiectasis. People can join the study if they produce sputum and have a history of flare-ups (also called exacerbations). The purpose of this study is to find out whether a medicine called BI 1291583 helps people with bronchiectasis. Participants are put into 4 groups randomly, which means by chance. Participants in groups 1, 2, and 3 get different doses of BI 1291583. Participants in group 4 get placebo. Placebo tablets look like BI 1291583 tablets, but do not contain any medicine. Participants take the tablets once a day. Participants are in the study for between 6 months and 1 year. During this time, they visit the study site about 10 times and get about 5 phone calls from the site staff. The doctors document when participants experience flare-ups during the study. The time to the first flare-ups is compared between the treatment groups. Doctors also regularly check participants' health and take note of any unwanted effects.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (112)

Phoenix Medical GroupPeoria, Arizona, United States
Newport Native MD, IncNewport Beach, California, United States
University of California DavisSacramento, California, United States
Central Florida Pulmonary GroupAltamonte Springs, Florida, United States
Malcom Randall VA Medical CenterGainesville, Florida, United States
University of Florida College of MedicineJacksonville, Florida, United States
University of Kansas Medical CenterKansas City, Kansas, United States
New York University Langone Medical CenterNew York, New York, United States
NewYork-Presbyterian/Weill Cornell Medical CenterNew York, New York, United States
Southeastern Research CenterWinston-Salem, North Carolina, United States
University of CincinnatiCincinnati, Ohio, United States
Medical University of South CarolinaCharleston, South Carolina, United States

+ 100 more locations — full list on the registry record.

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