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Study identifier: NCT05231655 Synced from ClinicalTrials.gov · August 05, 2026
● Recruiting

Ex VIvo DEtermiNed Cancer Therapy

Condition: Bladder Cancer · Kidney Cancer · Melanoma  ·  Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust

PhaseN/A
Planned participants600
Who can joinAll sexes, 16 Years to no upper limit
Healthy volunteersNo

About this study

EVIDENT's aim is to test if ex vivo drug screening can predict whether patients with solid cancers will respond, or not respond, to standard care treatments. Patients undergoing standard care surgery to excise their tumour, those undergoing a biopsy, or those having a fluid aspirate of a solid tumour with surplus tissue available after diagnostic use will be eligible for this study. The specimen will then be assessed with ex vivo drug screening utilising all standard therapies and therapies that are more novel and in early stages of development. The results of the ex vivo drug screen will be compared to the cancer's actual response to standard care treatments for those that undergo therapy to determine how effective the test is at predicting treatment response.

This description comes directly from the study's public registry record.

Talk to the study team

Greg Wells, PhD  ·  +44 114 215 9098  ·  g.wells@sheffield.ac.uk

Always discuss trial participation with your own doctor first.

Locations (1)

Sheffield Teaching Hospitals NHS Foundation TrustSheffield, South Yorkshire, United KingdomRecruiting

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