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Study identifier: NCT05220137 Synced from ClinicalTrials.gov · August 04, 2026
● Completed

Using the Multiphase Optimization Strategy to Adapt Cognitive Processing Therapy

Condition: Stress Disorders, Post-Traumatic  ·  Sponsor: VA Office of Research and Development

PhaseNA
Planned participants271
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Cognitive Processing Therapy (CPT) consists of discrete therapeutic components that are delivered across 12 sessions, but most Veterans never reach session 12, and those who drop out receive only 4 sessions on average. Veterans drop out because of time constraints, logistics, and lack of perceived benefit. Unfortunately, Veterans who drop out prematurely may never receive the most effective components of CPT and continue to experience symptom-related distress and numerous other negative outcomes, including lost productivity, substance use, later-life physical disability, reduced quality of life, and increased risk of suicide. The overall objective of this study is to adapt CPT into a brief, effective format. The rationale is that identifying the most effective intervention components and delivering only those components will make CPT deliverable in a shorter timeframe, thus improving efficiency, reducing drop-out related to poor treatment response, and ensuring that Veterans receive the most beneficial components of treatment, which will significantly improve their quality of life.

This description comes directly from the study's public registry record.

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No contact information is available for this study as per the public registry record.

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Locations (3)

VA Ann Arbor Healthcare System, Ann Arbor, MIAnn Arbor, Michigan, United States
Cincinnati VA Medical Center, Cincinnati, OHCincinnati, Ohio, United States
VA Salt Lake City Health Care System, Salt Lake City, UTSalt Lake City, Utah, United States

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