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A Study of Encorafenib Plus Cetuximab Taken Together With Pembrolizumab Compared to Pembrolizumab Alone in People With Previously Untreated Metastatic Colorectal Cancer
Condition: Metastatic Colorectal Cancer · Sponsor: Pfizer
About this study
The purpose of this study is to learn about the effects of three study medicines (encorafenib, cetuximab, and pembrolizumab) given together for the treatment of colorectal cancer that: * is metastatic (spread to other parts of the body); * has the condition of genetic hypermutability (tendency to mutation) or impaired DNA mismatch repair (MMR) * has a certain type of abnormal gene called "BRAF" and; * has not received prior treatment. All participants in this study will receive pembrolizumab at the study clinic as an intravenous (IV) infusion (given directly into a vein) at the study clinic. In addition, half of the participants will take encorafenib by mouth at home every day and cetuximab by IV infusion at the study clinic. The study team will monitor how each participant is doing with the study treatment during regular visits at the study clinic.
This description comes directly from the study's public registry record.
Talk to the study team
No contact information is available for this study as per the public registry record.
Always discuss trial participation with your own doctor first.
Locations (59)
| Mayo Clinic Building - Phoenix | Phoenix, Arizona, United States | — |
| Mayo Clinic Hospital | Phoenix, Arizona, United States | — |
| Mayo Clinic | Scottsdale, Arizona, United States | — |
| Mount Sinai Cancer Center | Miami Beach, Florida, United States | — |
| The West Clinic, PLLC dba West Cancer Center | Germantown, Tennessee, United States | — |
| MD Anderson Cancer Center | Houston, Texas, United States | — |
| Austin Health | Heidelberg, Victoria, Australia | — |
| Peter MacCallum Cancer Centre | Melbourne, Victoria, Australia | — |
| Royal Melbourne Hospital | Parkville, Victoria, Australia | — |
| Imelda General Hospital | Bonheiden, Antwerpen, Belgium | — |
| Institut Jules Bordet | Anderlecht, Bruxelles-capitale, Région de, Belgium | — |
| Cliniques universitaires Saint-Luc | Brussels, Bruxelles-capitale, Région de, Belgium | — |
+ 47 more locations — full list on the registry record.
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