EichorEICHOR
Study identifier: NCT05198934 Synced from ClinicalTrials.gov · August 04, 2026
● Completed

Sotorasib and Panitumumab Versus Investigator's Choice for Participants With Kirsten Rat Sarcoma (KRAS) p.G12C Mutation

Condition: Colorectal Cancer (CRC)  ·  Sponsor: Amgen

PhasePhase 3
Planned participants160
Who can joinAll sexes, 18 Years to 100 Years
Healthy volunteersNo

About this study

The aim of the study is to compare progression-free survival (PFS) in previously treated participants with Kirsten rat sarcoma (KRAS) p.G12C mutated colorectal cancer (CRC) receiving sotorasib 240 mg once daily (QD) and panitumumab vs investigator's choice (trifluridine and tipiracil, or regorafenib), and sotorasib 960 mg QD and panitumumab vs investigator's choice (trifluridine and tipiracil, or regorafenib).

This description comes directly from the study's public registry record.

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No contact information is available for this study as per the public registry record.

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Locations (105)

Central Alabama ResearchBirmingham, Alabama, United States
City of Hope National Medical CenterDuarte, California, United States
University of California IrvineOrange, California, United States
Johns Hopkins University School of MedicineWashington D.C., District of Columbia, United States
Cancer Specialists of North FloridaJacksonville, Florida, United States
Lakes Research LLCMiami Lakes, Florida, United States
Northwest Georgia Oncology Centers PCMarietta, Georgia, United States
University of MichiganAnn Arbor, Michigan, United States
Revive Research InstituteFarmington Hills, Michigan, United States
Sparrow Clinical Research InstituteLansing, Michigan, United States
Revive Research InstituteSterling Heights, Michigan, United States
Upstate University HospitalSyracuse, New York, United States

+ 93 more locations — full list on the registry record.

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