EichorEICHOR
Study identifier: NCT05171647 Synced from ClinicalTrials.gov · August 02, 2026
● Active Not Recruiting

A Study Evaluating Efficacy and Safety of Mosunetuzumab in Combination With Polatuzumab Vedotin Compared to Rituximab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed or Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma

Condition: Non-Hodgkin Lymphoma  ·  Sponsor: Hoffmann-La Roche

PhasePhase 3
Planned participants208
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study will assess the efficacy and safety of mosunetuzumab in combination with polatuzumab vedotin (M+P) in participants with relapsed or refractory (R/R) diffuse-large B-cell lymphoma (DLBCL), high-grade B-cell lymphoma, transformed follicular lymphoma (trFL) and FL Grade 3B (FL3B) in comparison with a commonly used regimen in this participant population, rituximab, gemcitabine and oxaliplatin (R-GemOx).

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (52)

City of Hope Cancer CenterDuarte, California, United States
St. Luke's HospitalChesterfield, Missouri, United States
Ascension Seton Infusion CenterAustin, Texas, United States
MD Anderson Cancer CenterHouston, Texas, United States
Hospital AlemanBuenos Aires, Argentina
Instituto Alexander FlemingBuenos Aires, Argentina
FUNDALEUBuenos Aires, Argentina
Hospital Italiano de Buenos AiresCiudad Autonoma Buenos Aires, Argentina
Hospital Erasto GaertnerCuritiba, Paraná, Brazil
Hospital das Clinicas - UFRGSPorto Alegre, Rio Grande do Sul, Brazil
Hospital das Clínicas FMRP-USPRibeirão Preto, São Paulo, Brazil
Hospital Sao JoseSão Paulo, São Paulo, Brazil

+ 40 more locations — full list on the registry record.

Follow this study

Save your interest here for when the public record changes — results posted, or the study's status changes. Email alerts for this study aren't switched on yet.

We keep this only about this public record, and never email you without alerts being switched on. Want it removed at any time? Email hello@eichor.com. Never medical advice. By subscribing you agree to our Terms of Use and Privacy Policy.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →