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Study identifier: NCT05153239 Synced from ClinicalTrials.gov · August 02, 2026
● Completed

Clinical Trial of Lurbinectedin as Single-agent or in Combination With Irinotecan Versus Topotecan or Irinotecan in Patients With Relapsed Small-cell Lung Cancer (LAGOON)

Condition: Relapsed Small Cell Lung Cancer  ·  Sponsor: PharmaMar

PhasePhase 3
Planned participants705
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Multicenter, open-label, randomized, controlled phase III clinical trial to evaluate and compare the activity and safety of two experimental arms consisting of lurbinectedin as single agent (Group A) or the combination of lurbinectedin with irinotecan (Group B) versus Investigator's Choice (topotecan or irinotecan) as control arm (Group C), in Small-cell Lung Cancer (SCLC) patients who failed one prior platinum-containing line.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (210)

Ironwood Cancer & Research CentersChandler, Arizona, United States
Genesis Cancer and BloodHot Springs, Arkansas, United States
Florida Cancer Specialists - SouthFort Myers, Florida, United States
Florida Cancer Specialists - NorthSt. Petersburg, Florida, United States
Florida Cancer Specialists - PanhandleTallahassee, Florida, United States
Florida Cancer Specialists - EastWest Palm Beach, Florida, United States
Duly Health and CareJoliet, Illinois, United States
Norton Cancer Institue, DowntownLouisville, Kentucky, United States
Dana-Farber Cancer InstituteBoston, Massachusetts, United States
Oncology Hematology West, PC (Grand Island)Grand Island, Nebraska, United States
Oncology Hematology West, PC dba Nebraska Cancer SpecialistsOmaha, Nebraska, United States
FirstHealth Outpatient Cancer CenterPinehurst, North Carolina, United States

+ 198 more locations — full list on the registry record.

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