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Study identifier: NCT05117840 Synced from ClinicalTrials.gov · August 03, 2026
● Active Not Recruiting

Screening for High Frequency Malignant Disease

Condition: Lung Cancer  ·  Sponsor: Guardant Health, Inc.

PhaseN/A
Planned participants12000
Who can joinAll sexes, 50 Years to 80 Years
Healthy volunteersYes

About this study

The SHIELD (Screening for High Frequency Malignant Disease) study is a prospective, observational, multi-site basket design trial without randomization. The primary objective of the study is to evaluate the sensitivity and specificity of a blood-based GuardantLUNAR-2 test to detect high frequency cancer in screen-relevant populations.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (143)

University of Alabama Birmingham Lung Health CenterBirmingham, Alabama, United States
Highlands Oncology Group PAFayetteville, Arkansas, United States
Pacific Cancer Medical CenterAnaheim, California, United States
Providence St. Joseph Hospital Eureka Cancer ProgramEureka, California, United States
SoCal Clinical ResearchFountain Valley, California, United States
Advanced Investigative MedicineHawthorne, California, United States
Cedars-Sinai Medical CenterLos Angeles, California, United States
California Medical Research Associates Inc.Northridge, California, United States
Providence Medical FoundationSanta Rosa, California, United States
Starling PhysiciansNew Britain, Connecticut, United States
George Washington University Medical CenterWashington D.C., District of Columbia, United States
Central Florida Pulmonary Group, P.A.Altamonte Springs, Florida, United States

+ 131 more locations — full list on the registry record.

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