EichorEICHOR
Study identifier: NCT05111626 Synced from ClinicalTrials.gov · August 02, 2026
● Terminated

Bemarituzumab Plus Chemotherapy and Nivolumab Versus Chemotherapy and Nivolumab for FGFR2b Overexpressed Untreated Advanced Gastric and Gastroesophageal Junction Cancer.

Condition: Gastric Cancer · Gastroesophageal Junction Adenocarcinoma  ·  Sponsor: Amgen

PhasePhase 3
Planned participants515
Who can joinAll sexes, 18 Years to 100 Years
Healthy volunteersNo

About this study

The main objective of Part 1 is to evaluate the safety and tolerability of bemarituzumab plus 5-fluorouracil, leucovorin, and oxaliplatin (mFOLFOX6) and nivolumab. The main objective Part 2 is to compare efficacy of bemarituzumab plus chemotherapy (mFOLFOX6 or capecitabine combined with oxaliplatin (CAPOX)) and nivolumab to placebo plus chemotherapy (mFOLFOX6 or CAPOX) and nivolumab as assessed by overall survival.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (348)

Mayo Clinic - ArizonaPhoenix, Arizona, United States
The Oncology Institute Clinical ResearchCerritos, California, United States
Cancer and Blood Specialty ClinicDowney, California, United States
City of Hope National Medical CenterDuarte, California, United States
University of California Los AngelesLos Angeles, California, United States
University of California IrvineOrange, California, United States
Torrance Memorial Physician NetworkRedondo Beach, California, United States
Translational Research in Oncology - US IncSanta Monica, California, United States
Translational Research in Oncology US Inc, Trio Central PharmacySanta Monica, California, United States
Olive View-University of California in Los Angeles Medical CenterSylmar, California, United States
Presbyterian Intercommunity Hospital Health Whitter HospitalWhittier, California, United States
Yale New Haven Hospital Yale Cancer CenterNew Haven, Connecticut, United States

+ 336 more locations — full list on the registry record.

Follow this study

Save your interest here for when the public record changes — results posted, or the study's status changes. Email alerts for this study aren't switched on yet.

We keep this only about this public record, and never email you without alerts being switched on. Want it removed at any time? Email hello@eichor.com. Never medical advice. By subscribing you agree to our Terms of Use and Privacy Policy.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →