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Study identifier: NCT05078047 Synced from ClinicalTrials.gov · August 03, 2026
● Active Not Recruiting

Study Comparing the Standard Administration of IO Versus the Same IO Administered Each 3 Months in Patients in Response After 6 Months of Standard IO

Condition: Lung Cancer Metastatic · Renal Cell Carcinoma · Head and Neck Cancer  ·  Sponsor: UNICANCER

PhasePhase 3
Planned participants646
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Immunotherapy (IO), such as treatment with anti-PD-1, PD-L1, or CTLA-4 inhibitors, is a rapidly expanding treatment for multiple metastatic cancers with improved survival for certain cancers. However, the optimal duration of immunotherapies is currently unknown. Our hypothesis is that a reduced dose intensity of IO could be as effective as the current standard treatment in term of prevention of the disease progression. If proved right, this study will have a positive medico-economic impact by reduction of the costs associated with the treatment and the toxicity, and an increase of the patients' quality of life.

This description comes directly from the study's public registry record.

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No contact information is available for this study as per the public registry record.

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Locations (33)

Institut de cancérologie de l'OuestAngers, France
Clinique Sainte CatherineAvignon, France
Centre Hospitalier de la Côte BasqueBayonne, France
CHU Bordeaux - Hôpial Saint AndréBordeaux, France
CH Boulogne sur MerBoulogne-sur-Mer, France
Centre François BaclesseCaen, France
Centre Jean PerrinClermont-Ferrand, France
Centre Hospitalier IntercommunalCréteil, France
CHU Henri MondorCréteil, France
Centre Georges François LeclercDijon, France
GH Mutualiste de GrenobleGrenoble, France
CHD VendéeLa Roche-sur-Yon, France

+ 21 more locations — full list on the registry record.

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