A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants
Condition: Lupus Nephritis · Sponsor: Hoffmann-La Roche
About this study
This phase II, randomized, double-blind, placebo-controlled study is designed to evaluate the safety, efficacy and pharmacokinetics (PK) of obinutuzumab in adolescent participants (AP) aged 12 to less than 18 with biopsy-confirmed proliferative lupus nephritis (LN). It will also evaluate open label safety and PK of obinutuzumab in pediatric participants (PP), aged 5 to \<12 with LN.
This description comes directly from the study's public registry record.
Talk to the study team
Reference Study ID Number: WA42985 https://forpatients.roche.com/ No attachments to email below. · 888-662-6728 (U.S. and Canada) · global.rochegenentechtrials@roche.com
Fastest response: use the inquiry form. https://www.gene.com/contact-us/submit-medical-inquiry
Always discuss trial participation with your own doctor first.
Locations (43)
| Loma Linda University health | Loma Linda, California, United States | Recruiting |
| UCSF Benioff Childrens Hospital | San Francisco, California, United States | Recruiting |
| Children's Hospital Colorado, Anchutz Medical Campus | Aurora, Colorado, United States | Recruiting |
| Emory Children's Center | Atlanta, Georgia, United States | Recruiting |
| Indiana University Health University Hospital | Indianapolis, Indiana, United States | Recruiting |
| Louisiana State University | Shreveport, Louisiana, United States | Recruiting |
| Hackensack University Medical Center | Hackensack, New Jersey, United States | Recruiting |
| Cohen Children's Medical Center of New York | Queens, New York, United States | Recruiting |
| Cincinnati Childrens Hospital | Cincinnati, Ohio, United States | Recruiting |
| Chldren?s Hospital of Philadelphia | Philadelphia, Pennsylvania, United States | Withdrawn |
| Texas Arthritis Center | El Paso, Texas, United States | Withdrawn |
| Ser Servicos Especializados Em Reumatologia | Salvador, Estado de Bahia, Brazil | Recruiting |
+ 31 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT05039619