Natural History Study in Adult-Onset Leukoencephalopathy With Axonal Spheroids and Pigmented Glia
Condition: ALSP · Sponsor: Vigil Neuroscience, Inc.
About this study
Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) is a rare, rapidly progressing, genetic, neurodegenerative disease for which no definitive treatment options and limited information on the natural history of the disease are available. The structural, genetic, and neuropathophysiological abnormalities of ALSP lead to the onset of neurologic symptoms, such as moderate to severe motor and neuropsychiatric impairments. This natural history study will collect data to contribute to the development of future novel therapies that focus on the neuropathophysiological features that underlie ALSP and that are essential to reverse, delay, or stop progression of this debilitating disorder.
This description comes directly from the study's public registry record.
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No contact information is available for this study as per the public registry record.
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Locations (12)
| Investigative Site 4 | San Francisco, California, United States | — |
| Investigative Site 5 | Englewood, Colorado, United States | — |
| Investigative Site 1 | Boca Raton, Florida, United States | — |
| Investigative Site 2 | Jacksonville, Florida, United States | — |
| Investigative Site 11 | Boston, Massachusetts, United States | — |
| Investigative Site 10 | Philadelphia, Pennsylvania, United States | — |
| Investigative Site 12 | São Paulo, Brazil | — |
| Investigative Site 3 | London, Ontario, Canada | — |
| Investigative Site 8 | Leipzig, Germany | — |
| Investigative Site 9 | Tübingen, Germany | — |
| Investigative Site 6 | Amsterdam, Netherlands | — |
| Investigative Site 7 | London, United Kingdom | — |
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Source record: clinicaltrials.gov/study/NCT05020743