EichorEICHOR
Study identifier: NCT04975308 Synced from ClinicalTrials.gov · August 03, 2026
● Active Not Recruiting

A Study of Imlunestrant, Investigator's Choice of Endocrine Therapy, and Imlunestrant Plus Abemaciclib in Participants With ER+, HER2- Advanced Breast Cancer

Condition: Breast Neoplasms · Neoplasm Metastasis  ·  Sponsor: Eli Lilly and Company

PhasePhase 3
Planned participants874
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The main purpose of this study is to measure how well imlunestrant works compared to standard hormone therapy, and how well imlunestrant with abemaciclib work compared to imlunestrant in participants with breast cancer that is estrogen receptor positive (ER+) and human epidermal receptor 2 negative (HER2-). Participants must have breast cancer that is advanced or has spread to another part of the body. Study participation could last up to 5 years.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (243)

Ironwood Cancer & Research CentersChandler, Arizona, United States
Banner MD Anderson Cancer CenterGilbert, Arizona, United States
Marin Cancer CareGreenbrae, California, United States
University of California Davis (UC Davis) Comprehensive Cancer CenterSacramento, California, United States
Sharp Memorial HospitalSan Diego, California, United States
Banner MD Anderson Cancer Center at McKee Medical CenterLoveland, Colorado, United States
Clermont Oncology CenterClermont, Florida, United States
University of Florida College of MedicineGainesville, Florida, United States
Mid Florida Hematology and Oncology CenterOrange City, Florida, United States
Florida Cancer SpecialistsSarasota, Florida, United States
Florida Cancer SpecialistsSt. Petersburg, Florida, United States
Kaiser Permanente Moanalua Medical CenterHonolulu, Hawaii, United States

+ 231 more locations — full list on the registry record.

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