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Study identifier: NCT04955899 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Safety of Splenic Stimulation for RA

Condition: Rheumatoid Arthritis  ·  Sponsor: Galvani Bioelectronics

PhaseNA
Planned participants5
Who can joinAll sexes, 22 Years to 75 Years
Healthy volunteersNo

About this study

This study will evaluate the safety and tolerability of stimulating the splenic neurovascular bundle (NVB) with the Galvani System, which consists of a lead, implantable pulse generator, external components and accessories. Participants eligible for implant will have active rheumatoid arthritis (RA) and have an inadequate response or intolerance to at least two biologic Disease Modifying Anti-Rheumatic Drugs (DMARDs) or JAK inhibitors (JAKis). Five participants will be implanted with the device and receive neurostimulation for 12 weeks.

This description comes directly from the study's public registry record.

Talk to the study team

Operations Director  ·  +44 (0)800 3688514  ·  clinical@galvani.bio

Always discuss trial participation with your own doctor first.

Locations (2)

Academic Medical Center (AMC) Dept of Rheumatology & Clinical ImmunologyAmsterdam, NetherlandsRecruiting
Greater Glasgow Health BoardGlasgow, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT04955899