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Study identifier: NCT04939090 Synced from ClinicalTrials.gov · August 05, 2026
● Active Not Recruiting

Olanzapine Versus Megestrol Acetate for the Treatment of Loss of Appetite Among Advanced Cancer Patients

Condition: Advanced Malignant Solid Neoplasm · Anorexia · Hematopoietic and Lymphoid Cell Neoplasm  ·  Sponsor: Alliance for Clinical Trials in Oncology

PhasePhase 3
Planned participants227
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This phase III trial compares the effects of olanzapine versus megestrol acetate in treating loss of appetite in patients with cancer that has spread to other places in the body (advanced). Olanzapine may stimulate and increase appetite. This study aims to find out if olanzapine is better than the usual approach (megestrol acetate) for stimulating appetite and preventing weight loss.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (293)

Arizona Center for Cancer Care - GilbertGilbert, Arizona, United States
CTCA at Western Regional Medical CenterGoodyear, Arizona, United States
Arizona Center for Cancer Care-PeoriaPeoria, Arizona, United States
Arizona Center for Cancer Care - PhoenixPhoenix, Arizona, United States
Arizona Center for Cancer Care - OsbornScottsdale, Arizona, United States
Arizona Center for Cancer Care - ScottsdaleScottsdale, Arizona, United States
Arizona Center for Cancer Care-SurpriseSurprise, Arizona, United States
NEA Baptist Memorial Hospital and Fowler Family Cancer Center - JonesboroJonesboro, Arkansas, United States
Epic Care-DublinDublin, California, United States
Epic Care Partners in Cancer CareEmeryville, California, United States
Washington HospitalFremont, California, United States
Contra Costa Regional Medical CenterMartinez, California, United States

+ 281 more locations — full list on the registry record.

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