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Study identifier: NCT04924205 Synced from ClinicalTrials.gov · July 29, 2026
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A Comparison Of Primary TKA Rehabilitation Using A Smart Orthotic Versus Outpatient Physical Therapy

Condition: Arthropathy of Knee  ·  Sponsor: Nicolas Noiseux, MD, MS, FRCSC

PhaseNA
Planned participants80
Who can joinAll sexes, 18 Years to 100 Years
Healthy volunteersNo

About this study

This will be a prospective, randomized, noninferiority clinical trial comparing rehabilitation methods post-total knee arthroplasty (TKA). Population of interest is adult hip/knee clinic patients over age 18 who are indicated for unilateral primary total knee arthroplasty. All TKA patients are prescribed physical therapy (PT) for rehabilitation post-operatively. The investigators will compare this current treatment with a new, validated, wearable smart knee brace (FM2 Knee Brace) that can be used for rehabilitation post-TKA. Following enrollment in the study, the investigators will match and randomize participants into two cohorts (outpatient PT versus FM2 Knee Brace). Outpatient PT group will be prescribed routine six-week course of outpatient PT (no pool exercises, remainder at therapist's discretion) to start as soon as possible upon discharge. The FM2 Knee Brace group will complete device set up at pre-op visit and will be prescribed 3-4 exercises to complete at their discretion over six weeks. The investigators will collect measurements of knee flexion, extension, total arc of motion at pre-op visit and at 6-week, 3-month, and 1-year post-op visits. The investigators will also plan to record additional PROs, therapy compliance, and complication rates. The investigators will compare the two groups to test whether the new FM2 Knee Brace is noninferior to regular PT when recovering from TKA, and if the new technology could be an alternative to outpatient PT.

This description comes directly from the study's public registry record.

Talk to the study team

Lauren Crowe, BS  ·  319-467-7128  ·  lauren-keitel@uiowa.edu

Kyle Geiger, MD  ·  kyle-geiger@uiowa.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Iowa Hospitals & ClinicsIowa City, Iowa, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04924205