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Study identifier: NCT04891640 Synced from ClinicalTrials.gov · August 05, 2026
● Completed

Biologic Abatement and Capturing Kids' Outcomes and Flare Frequency in Juvenile Spondyloarthritis

Condition: Juvenile Spondyloarthritis  ·  Sponsor: Children's Hospital of Philadelphia

PhasePhase 4
Planned participants164
Who can joinAll sexes, 8 Years to 21 Years
Healthy volunteersNo

About this study

This randomized pragmatic trial will generate knowledge about strategies used to de-escalate tumor necrosis factor inhibitor (TNFi) therapy in patients with juvenile spondyloarthritis with sustained inactive disease and are treated at one of the 31 participating pediatric healthcare systems. This open label study will be conducted in the setting of routine clinical care and will compare the risk and timing of flare (Aim 1) and patients' lived experiences (Aim 2) across three arms.

This description comes directly from the study's public registry record.

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No contact information is available for this study as per the public registry record.

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Locations (31)

University of Alabama at BirminghamBirmingham, Alabama, United States
Phoenix Children'sPhoenix, Arizona, United States
Children's Hospital Los AngelesLos Angeles, California, United States
Stanford UniversityPalo Alto, California, United States
Children's Hospital of ColoradoAurora, Colorado, United States
Nemours Children's HospitalWilmington, Delaware, United States
Children's National Health SystemWashington D.C., District of Columbia, United States
Nemours Children's HealthOrlando, Florida, United States
Children's Healthcare of AtlantaAtlanta, Georgia, United States
Ann & Robert H. Lurie Children's Hospital of ChicagoChicago, Illinois, United States
Riley Hospital for Children at IU HealthIndianapolis, Indiana, United States
University of Iowa Stead Family Children's HospitalIowa City, Iowa, United States

+ 19 more locations — full list on the registry record.

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