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Study identifier: NCT04862221 Synced from ClinicalTrials.gov · August 05, 2026
● Active Not Recruiting

TReatment for ImmUne Mediated PathopHysiology

Condition: Acute Liver Failure · Fulminant Hepatic Failure · Hepatic Encephalopathy  ·  Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

PhasePhase 2
Planned participants163
Who can joinAll sexes, 1 Year to 18 Years
Healthy volunteersNo

About this study

TReatment for ImmUne Mediated PathopHysiology (TRIUMPH) is a multi-center, three arm, randomized, controlled trial of immunosuppressive therapy for children with acute liver failure. The study will determine if suppressing inflammatory responses with either corticosteroids or equine anti-thymocyte globulin therapy improves survival for children with this rare, life-threatening condition.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (17)

Children's Hospital Los AngelesLos Angeles, California, United States
Lucile Packard Children's HospitalPalo Alto, California, United States
Rady Children's HospitalSan Diego, California, United States
Children's Hospital ColoradoAurora, Colorado, United States
Ann & Robert H. Lurie Children's Hospital of ChicagoChicago, Illinois, United States
Riley Hospital for ChildrenIndianapolis, Indiana, United States
Children's Hospital BostonBoston, Massachusetts, United States
The Children's Mercy HospitalKansas City, Missouri, United States
St. Louis Children's HospitalSt Louis, Missouri, United States
NYP Morgan Stanley Children's HospitalNew York, New York, United States
Cincinnati Children's Hospital Medical CenterCincinnati, Ohio, United States
The Children's Hospital of PhiladelphiaPhiladelphia, Pennsylvania, United States

+ 5 more locations — full list on the registry record.

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