EICHOR
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XB2001 in Combination With ONIVYDE + 5-FU/LV (+Folinic Acid) in Advanced Pancreatic Cancer
Condition: Pancreatic Cancer · Sponsor: XBiotech, Inc.
About this study
This trial will include 2 portions (phase 1 and phase 2). The first portion will be a Phase I, open label, dose escalation study to establish the maximum tolerated dose (MTD) of XB2001 as measured by Dose-Limiting Toxicity (DLT), in combination with ONIVYDE + LV + 5-FU chemotherapy regimen in patients with advanced pancreatic cancer and to determine the recommended dose for the subsequent Phase 2 study. The phase 2 portion will be implemented with the maximum established tolerated dose (MTD) of XB2001. The target enrollment in the phase 2 portion is 60 patients which will be randomized on a 1:1 basis to XB2001 plus ONIVYDE + LV + 5-FU (Arm 1) or placebo plus ONIVYDE + LV + 5-FU (Arm 2).
This description comes directly from the study's public registry record.
Talk to the study team
No contact information is available for this study as per the public registry record.
Always discuss trial participation with your own doctor first.
Locations (30)
| Arizona Oncology Associates | Tucson, Arizona, United States | — |
| Disney Family Cancer Center at Providence St. Joseph Medical Center | Burbank, California, United States | — |
| TOI Clinical Research | Cerritos, California, United States | — |
| Providence St. Joseph Heritage - Fullerton, CA | Fullerton, California, United States | — |
| Hoag Memorial Hospital Presbyterian | Newport Beach, California, United States | — |
| Grand Valley Oncology | Grand Junction, Colorado, United States | — |
| Sarah Cannon - Florida Cancer Specialists | Lake Mary, Florida, United States | — |
| Mt. Sinai Comprehensive Cancer Center | Miami Beach, Florida, United States | — |
| Sarasota Memorial Hospital | Sarasota, Florida, United States | — |
| Cleveland Clinic of Florida | Weston, Florida, United States | — |
| Goshen Center for Cancer Care | Goshen, Indiana, United States | — |
| Alliance for Multispecialty Research, LLC | Merriam, Kansas, United States | — |
+ 18 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT04825288