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Study identifier: NCT04819243 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

PALbociclib Endocrine Therapy Followed by Talazo Vs. Talazoz-Atezo Study

Condition: Premenopausal HR+/HER2- Metastatic Breast Cancer  ·  Sponsor: Samsung Medical Center

PhasePhase 2
Planned participants178
Who can joinAll sexes, 19 Years to no upper limit
Healthy volunteersNo

About this study

This study is a prospective, two-arm, randomized phase II study of talazoparib versus talazoparib plus atezolizumab in ER+ premeonopausal women with metastatic breast cancer harboring HRD scar 1st line treatment: GnRH agonist + Aromatase Inhibitor(AI) + Palbociclib 28 days after the last treatment of 1st line treatment(., randomization for 2nd line treatment is conducte to arm A(Talazoparib+Atezolizumab) and arm B(Talazoparib monotherapy)

This description comes directly from the study's public registry record.

Talk to the study team

Yeon Hee Park, phD  ·  +82-2-3410-1780  ·  yeonh.park@samsung.com

mieun Kim, CRA  ·  +82 2-2148-7664  ·  mieun2728.kim@samsung.com

Always discuss trial participation with your own doctor first.

Locations (1)

Samsung medical CenterSeoul, Gannam-gu, South KoreaRecruiting

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Source record: clinicaltrials.gov/study/NCT04819243