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Study identifier: NCT04790370 Synced from ClinicalTrials.gov · August 02, 2026
● Active Not Recruiting

Ultrasound-facilitated, Catheter-directed, Thrombolysis in Intermediate-high Risk Pulmonary Embolism

Condition: Pulmonary Embolism  ·  Sponsor: Boston Scientific Corporation

PhasePhase 4
Planned participants544
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

There are many available treatments for pulmonary embolism (PE), but the best treatment for this condition is not known. The HI-PEITHO study will compare two treatment options that are both available on the market for the treatment of PE. Patients will be randomized 1:1 to receive either blood thinners (anticoagulation) or blood thinners (anticoagulation) in combination with a device called the EkoSonicTM Endovascular device to dissolve blood clots. Patients will be followed for 12 months after randomization and have assessments while in the hospital as well as at 7 days, 30 days, 6 months and 12 months after randomization. The study will try to find out if one of these treatments is better than the other at reducing the risk of death and other serious problems.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

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Locations (60)

University of Alabama at BirminghamBirmingham, Alabama, United States
Cedars - Sinai Medical CenterLos Angeles, California, United States
Christiana HospitalNewark, Delaware, United States
Piedmont HospitalAtlanta, Georgia, United States
Emory University HospitalAtlanta, Georgia, United States
Augusta UniversityAugusta, Georgia, United States
Methodist HospitalsMerrillville, Indiana, United States
Baptist Health East LouisvilleLousville, Kentucky, United States
University of Maryland School of MedicineBaltimore, Maryland, United States
Massachusetts General HospitalBoston, Massachusetts, United States
University of Michigan HospitalsAnn Arbor, Michigan, United States
Henry Ford HospitalDetroit, Michigan, United States

+ 48 more locations — full list on the registry record.

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