Condition: Early Alzheimer's Disease · Sponsor: Novo Nordisk A/S
This study is done to find out whether the medicine, semaglutide, has a positive effect on early Alzheimer's disease. Participants will either get semaglutide or placebo (a "dummy" medicine which does not contain any study medicine) - which treatment participants get is decided by an equal chance. The study will last for up to 173 weeks (about 3 years and 4 months). Participants will have 17 clinic visits and 1 phone call with the study doctor. The study includes various tests and scans. At 10 of the clinic visits participants will have blood samples taken. Participants must have a study partner, who is willing to take part in the study. Women cannot take part if pregnant, breastfeeding or plan to become pregnant during the study period. A cerebrospinal fluid (CSF) sub-study will be performed as a part of the study. The sub-study will be performed on a selection of sites based on their experience with CSF sampling and willingness to participate in this sub-study. The endpoints related to this sub-study are exploratory only.
This description comes directly from the study's public registry record.
No contact information is available for this study as per the public registry record.
Always discuss trial participation with your own doctor first.
| Banner Alzheimer's Institute | Phoenix, Arizona, United States | — |
| Imaging Endpoints | Scottsdale, Arizona, United States | — |
| Banner Sun Health Research Institute | Sun City, Arizona, United States | — |
| Tucson Neuroscience Research | Tucson, Arizona, United States | — |
| Advanced Research Center, Inc. | Anaheim, California, United States | — |
| Fullerton Neurology and Headache Center | Fullerton, California, United States | — |
| Pacific Research Network | Lemon Grove, California, United States | — |
| Torrance Clin Res Inst, Inc. | Lomita, California, United States | — |
| ASCLEPES Research Centers, | Long Beach, California, United States | — |
| Cedars-Sinai Medical Center | Los Angeles, California, United States | — |
| UCLA_Los Angeles | Los Angeles, California, United States | — |
| Wr-Pri, Llc | Newport Beach, California, United States | — |
+ 435 more locations — full list on the registry record.
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