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Study identifier: NCT04770779 Synced from ClinicalTrials.gov · August 02, 2026
● Active Not Recruiting

A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-TDT)

Condition: Transfusion-dependent Alpha-Thalassemia · Transfusion-dependent Beta-Thalassemia  ·  Sponsor: Agios Pharmaceuticals, Inc.

PhasePhase 3
Planned participants258
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The primary objective of this study was to compare the effect of mitapivat versus placebo on transfusion burden in participants with α- or β-transfusion-dependent thalassemia.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (75)

Phoenix Children's HospitalPhoenix, Arizona, United States
San Diego Hospital, UC San Diego HealthLa Jolla, California, United States
Children's Hospital OaklandOakland, California, United States
Stanford MedicinePalo Alto, California, United States
Boston Children's HospitalBoston, Massachusetts, United States
Children's Hospital of MichiganDetroit, Michigan, United States
Weill Cornell Medical CenterNew York, New York, United States
Duke University Medical CenterDurham, North Carolina, United States
Penn Medicine - University of Pennsylvania Health SystemPhiladelphia, Pennsylvania, United States
Seattle Cancer Care Alliance, University of WashingtonSeattle, Washington, United States
Hospital Das Clínicas da Faculdade de Medicina de Ribeirão Preto - USPRibeirão Preto, Brazil
GSH Banco de Sangue de São PauloSão Paulo, Brazil

+ 63 more locations — full list on the registry record.

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