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Study identifier: NCT04770753 Synced from ClinicalTrials.gov · August 02, 2026
● Active Not Recruiting

A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Non-Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-NTDT)

Condition: Non-Transfusion-dependent Alpha-Thalassemia · Non-Transfusion-dependent Beta-Thalassemia  ·  Sponsor: Agios Pharmaceuticals, Inc.

PhasePhase 3
Planned participants194
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The primary purpose of this study was to compare the effect of mitapivat versus placebo on hemolytic anemia in participants with alpha- or beta-non-transfusion dependent thalassemia (NTDT).

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (68)

San Diego Hospital, UC San Diego HealthLa Jolla, California, United States
Stanford MedicinePalo Alto, California, United States
Massachusetts General HospitalBoston, Massachusetts, United States
Weill Cornell Medical CenterNew York, New York, United States
Duke University Medical CenterDurham, North Carolina, United States
Penn Medicine - University of Pennsylvania Health SystemPhiladelphia, Pennsylvania, United States
Universidade de Caxias do SulCaxias do Sul, Brazil
Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto - USPRibeirão Preto, Brazil
HEMORIO Instituto Nacional de HematologiaRio de Janeiro, Brazil
Praxis Pesquisa MedicaSanto André, Brazil
GSH Banco de Sangue de São PauloSão Paulo, Brazil
Instituto do Cancer do Estado de São Paulo, Hospital das Clínicas da Faculdade de Medicina da Universidad de São PauloSão Paulo, Brazil

+ 56 more locations — full list on the registry record.

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