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Study identifier: NCT04770545 Synced from ClinicalTrials.gov · August 03, 2026
● Completed

An Extension Study to Evaluate the Long-term Safety and Efficacy of Pegcetacoplan (APL-2) in Subjects With Geographic Atrophy Secondary to AMD

Condition: Geographic Atrophy Secondary to Age-related Macular Degeneration  ·  Sponsor: Apellis Pharmaceuticals, Inc.

PhasePhase 3
Planned participants792
Who can joinAll sexes, 60 Years to no upper limit
Healthy volunteersNo

About this study

This is a phase 3, open-label, multicenter, extension study to evaluate the long-term safety and efficacy of pegcetacoplan (APL-2) in subjects with geographic atrophy (GA) secondary to age-related macular degeneration (AMD) who participated in Study APL2-103 (NCT03777332) or completed the treatment at Month 24 of either Study APL2-303 (Derby, NCT03525613) or Study APL2-304 (Oaks, NCT03525600).

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

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Locations (175)

Retinal Research Institue, LLCPhoenix, Arizona, United States
Associated Retina Consultants, Ltd.Phoenix, Arizona, United States
California Retina ConsultantsBakersfield, California, United States
Retinal Diagnostic CenterCampbell, California, United States
The Retina PartnersEncino, California, United States
Retina Consultants of Orange CountyFullerton, California, United States
Atlantis EyecareHuntington Beach, California, United States
Jacobs Retina Center, UCSDLa Jolla, California, United States
Doheny Eye Center UCLALos Angeles, California, United States
Northern California Retina Vitreous AssociatesMountain View, California, United States
Retina Institute of California Medical GroupPalm Desert, California, United States
Byers Eye Institute, Stanford UniversityPalo Alto, California, United States

+ 163 more locations — full list on the registry record.

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