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Study identifier: NCT04745403 Synced from ClinicalTrials.gov · August 03, 2026
● Recruiting

Redirected HBV-Specific T Cells in Patients With HBV-related HCC (SAFE-T-HBV)

Condition: Hepatocellular Carcinoma  ·  Sponsor: Lion TCR Pte. Ltd.

PhasePhase 1
Planned participants10
Who can joinAll sexes, 21 Years to 75 Years
Healthy volunteersNo

About this study

This is a single center, single arm and open-label study to determine the safety of mRNA modified HBV-TCR redirected T-cells and to analyze the changes in tumor microenvironment caused by these HBV-TCR redirected T-cells in subjects with HBV-related HCC who are not amenable to/failed conventional treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Royce Fam  ·  69260818  ·  royce.fam@liontcr.com

Always discuss trial participation with your own doctor first.

Locations (1)

Singapore General HospitalSingapore, SingaporeRecruiting

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