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Study identifier: NCT04722887 Synced from ClinicalTrials.gov · August 01, 2026
● Completed

A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Two Different Doses of Alpha1-Proteinase Inhibitor Subcutaneous (Human) 15% in Participants With Alpha1-Antitrypsin Deficiency

Condition: Alpha1-Antitrypsin Deficiency  ·  Sponsor: Grifols Therapeutics LLC

PhasePhase 1/Phase 2
Planned participants17
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the safety and tolerability of 72 milligrams per kilogram (mg/kg) and 180 mg/kg Alpha-1 15%, administered as a single-dose subcutaneous (SC) infusion and subsequently as weekly SC infusions over 8 weeks in participants with Alpha1-Antitrypsin Deficiency (AATD).

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (5)

UCLA Medical CenterLos Angeles, California, United States
University of FloridaGainesville, Florida, United States
University of MiamiMiami, Florida, United States
Cleveland ClinicCleveland, Ohio, United States
Medical University of South Carolina - Children's HospitalCharleston, South Carolina, United States

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Source record: clinicaltrials.gov/study/NCT04722887