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Study identifier: NCT04708418 Synced from ClinicalTrials.gov · August 02, 2026
● Active Not Recruiting

A Study Evaluating Whether Pembrolizumab Alone or in Combination With CMP-001 Improves Efficacy of Treatment in Patients With Operable Melanoma

Condition: Clinical Stage III Cutaneous Melanoma AJCC v8 · Melanoma of Unknown Primary · Pathologic Stage IIIB Cutaneous Melanoma AJCC v8  ·  Sponsor: National Cancer Institute (NCI)

PhasePhase 2
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This phase II trial studies the effect of pembrolizumab alone or in combination with CMP-001 in treating patients with melanoma that can be treated by surgery (operable). Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Immunotherapy with CMP-001 may induce changes in body's immune system and may interfere with the ability of tumor cells to grow and spread. The addition of CMP-001 to pembrolizumab could improve the ability of the immune system to shrink tumors and to prevent them from returning.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (188)

Anchorage Associates in Radiation MedicineAnchorage, Alaska, United States
Alaska Breast Care and Surgery LLCAnchorage, Alaska, United States
Alaska Oncology and Hematology LLCAnchorage, Alaska, United States
Alaska Women's Cancer CareAnchorage, Alaska, United States
Anchorage Oncology CentreAnchorage, Alaska, United States
Katmai Oncology GroupAnchorage, Alaska, United States
Providence Alaska Medical CenterAnchorage, Alaska, United States
Fairbanks Memorial HospitalFairbanks, Alaska, United States
Banner University Medical Center - TucsonTucson, Arizona, United States
University of Arizona Cancer Center-North CampusTucson, Arizona, United States
Mercy Hospital Fort SmithFort Smith, Arkansas, United States
Providence Saint Joseph Medical Center/Disney Family Cancer CenterBurbank, California, United States

+ 176 more locations — full list on the registry record.

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