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Study identifier: NCT04697628 Synced from ClinicalTrials.gov · August 03, 2026
● Completed

Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer

Condition: Cervical Cancer  ·  Sponsor: Seagen, a wholly owned subsidiary of Pfizer

PhasePhase 3
Planned participants502
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

This trial is being done to find out whether tisotumab vedotin works better than chemotherapy to treat cervical cancer. People in this study have cervical cancer that has spread to other parts of the body (metastatic) or has come back after being treated (recurrent). Participants in this trial will be randomly assigned to one of two groups. One group will be treated with tisotumab vedotin. Participants in the other group will get one of five different chemotherapy drugs (topotecan, vinorelbine, gemcitabine, pemetrexed, or irinotecan). Participants and their doctors will know which group they are in. Participants in the chemotherapy group will decide with their study doctor which drug they will take.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (211)

Arizona Oncology Associates, PC - HALGlendale, Arizona, United States
Arizona Oncology Associates P.C. - NAHOAPhoenix, Arizona, United States
Arizona Oncology Associates, PC - HALPhoenix, Arizona, United States
Arizona Oncology Associates, PC - HALScottsdale, Arizona, United States
Arizona Oncology Associates, PC - HALTempe, Arizona, United States
University of California Irvine HealthIrvine, California, United States
UC Irvine Health (Investigator Site File Location)Orange, California, United States
University of California Irvine HealthOrange, California, United States
Olive View - UCLA Medical CenterSylmar, California, United States
Yale University School of MedicineNew Haven, Connecticut, United States
Broward Health Medical CenterFort Lauderdale, Florida, United States
Georgia Cancer Center at Augusta UniversityAugusta, Georgia, United States

+ 199 more locations — full list on the registry record.

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