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Study identifier: NCT04657289 Synced from ClinicalTrials.gov · August 02, 2026
● Active Not Recruiting

A Study of the Efficacy, Safety, and Pharmacokinetics of a 36-Week Refill Regimen for the Port Delivery System With Ranibizumab in Patients With Neovascular Age-Related Macular Degeneration (Velodrome)

Condition: Neovascular Age-related Macular Degeneration (nAMD)  ·  Sponsor: Hoffmann-La Roche

PhasePhase 3
Planned participants451
Who can joinAll sexes, 50 Years to no upper limit
Healthy volunteersNo

About this study

Study WR42221 is a Phase IIIb, global, multicenter, randomized, visual assessor-masked study designed to assess the efficacy, safety, and pharmacokinetics of the Port Delivery System with ranibizumab (PDS) 100 mg/mL delivered every 36 weeks (Q36W) compared with every 24 weeks (Q24W) in patients with neovascular age-related macular degeneration (nAMD).

This description comes directly from the study's public registry record.

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No contact information is available for this study as per the public registry record.

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Locations (104)

Centro Oftalmologico Dr. Charles S.A.Capital Federal, Argentina
OftalmosCapital Federal, Argentina
Grupo Laser VisionRosario, Argentina
Eyeclinic Albury WodongaAlbury, New South Wales, Australia
Eye and Retina ConsultantsHurstville, New South Wales, Australia
Retina Associates LiverpoolLiverpool, New South Wales, Australia
Retina and Macula SpecialistsMiranda, New South Wales, Australia
Sydney Eye HospitalSydney, New South Wales, Australia
Sydney Retina Clinic and Day SurgerySydney, New South Wales, Australia
Queensland Eye InstituteWoolloongabba, Queensland, Australia
Centre For Eye Research AustraliaEast Melbourne, Victoria, Australia
Retina Specialists VictoriaRowville, Victoria, Australia

+ 92 more locations — full list on the registry record.

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