EICHOR
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Study of Pembrolizumab (MK-3475) in Combination With Adjuvant Chemotherapy With or Without Radiotherapy in Participants With Newly Diagnosed Endometrial Cancer After Surgery With Curative Intent (MK-3475-B21 / KEYNOTE-B21 / ENGOT-en11 / GOG-3053)
Condition: Endometrial Neoplasms · Sponsor: Merck Sharp & Dohme LLC
About this study
The purpose of this study is to compare pembrolizumab + adjuvant chemotherapy with placebo + adjuvant chemotherapy, with or without radiotherapy, with respect to disease-free survival (DFS) as assessed radiographically by the investigator or by histopathologic confirmation of suspected disease recurrence, and with respect to overall survival (OS). The primary hypotheses are that pembrolizumab + adjuvant chemotherapy is superior to placebo + adjuvant chemotherapy, with or without radiotherapy, with respect to DFS as assessed radiographically by the investigator or by histopathologic confirmation of suspected disease recurrence, and with respect to OS.
This description comes directly from the study's public registry record.
Talk to the study team
No contact information is available for this study as per the public registry record.
Always discuss trial participation with your own doctor first.
Locations (231)
| University of Alabama - Birmingham ( Site 3061) | Birmingham, Alabama, United States | — |
| University of South Alabama, Mitchell Cancer Institute ( Site 3058) | Mobile, Alabama, United States | — |
| HonorHealth Research Institute - Biltmore ( Site 3043) | Phoenix, Arizona, United States | — |
| Arizona Oncology Associates PC- HOPE ( Site 3049) | Tucson, Arizona, United States | — |
| UCSD Moores Cancer Center ( Site 3053) | La Jolla, California, United States | — |
| University Of Colorado ( Site 3051) | Aurora, Colorado, United States | — |
| Smilow Cancer Hospital at Yale New Haven ( Site 3070) | New Haven, Connecticut, United States | — |
| Mount Sinai Cancer Center ( Site 3081) | Miami Beach, Florida, United States | — |
| Northside Hospital ( Site 3036) | Atlanta, Georgia, United States | — |
| Northwestern Memorial Hospital ( Site 3044) | Chicago, Illinois, United States | — |
| Parkview Cancer Institute ( Site 3067) | Fort Wayne, Indiana, United States | — |
| Indiana University Melvin and Bren Simon Cancer Center ( Site 3071) | Indianapolis, Indiana, United States | — |
+ 219 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT04634877