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Study identifier: NCT04619004 Synced from ClinicalTrials.gov · August 02, 2026
● Active Not Recruiting

HERTHENA-Lung01: Patritumab Deruxtecan in Subjects With Metastatic or Locally Advanced EGFR-mutated Non-Small Cell Lung Cancer

Condition: Non-Small Cell Lung Cancer Metastatic · Non-Small Cell Lung Cancer With Mutation in Epidermal Growth Factor Receptor  ·  Sponsor: Daiichi Sankyo

PhasePhase 2
Planned participants277
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is designed to evaluate the antitumor activity of patritumab deruxtecan in participants with metastatic or locally advanced NSCLC with an activating EGFR mutation (exon 19 deletion or L858R) who have received and progressed on or after at least 1 EGFR TKI and 1 platinum-based chemotherapy-containing regimen.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (123)

Banner MD Anderson Cancer CenterGilbert, Arizona, United States
City of HopeDuarte, California, United States
Moores Cancer Center at the UC San Diego HealthLa Jolla, California, United States
Pacific Shores Medical GroupLong Beach, California, United States
USC Norris Comprehensive Cancer CenterLos Angeles, California, United States
University of California at IrvineOrange, California, United States
Cedars SinaiWest Hollywood, California, United States
University of Colorado Denver - Anschutz Medical CampusAurora, Colorado, United States
Florida Cancer Specialists - SouthFort Myers, Florida, United States
AdventHealth OrlandoOrlando, Florida, United States
Memorial Healthcare SystemPembroke Pines, Florida, United States
Florida Cancer Specialist-NorthSt. Petersburg, Florida, United States

+ 111 more locations — full list on the registry record.

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