Study identifier: NCT04560998 Synced from ClinicalTrials.gov · August 05, 2026
● Completed

A Research Study to Compare a Medicine Called Semaglutide Against Placebo in People With Peripheral Arterial Disease and Type 2 Diabetes

Condition: Diabetes Mellitus, Type 2 · Peripheral Arterial Disease  ·  Sponsor: Novo Nordisk A/S

PhasePhase 3
Planned participants792
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is done to see if semaglutide has an effect on walking ability compared with placebo (dummy medicine) in people with peripheral arterial disease (PAD) and type 2 diabetes. Participants will either get semaglutide or placebo ("dummy") medicine - which treatment participants get is decided by chance. Semaglutide is a medicine for type 2 diabetes that can be prescribed by doctors in some countries. Participants will get the study medicine (semaglutide or placebo) in a pre-filled pen for injection. Participants must inject it once a week into the stomach area, thigh, or upper arm, at any time of the day. The study will last for about 59 weeks. Participants will have 8 clinic visits and 1 phone call with the study doctor. At some clinic visits, participants will have blood tests. At some visits participants will also do a treadmill test to measure how far they can walk. Women cannot take part if pregnant, breast-feeding or planning to become pregnant during the study period.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (283)

Cardiology, PCBirmingham, Alabama, United States
Cardiovascular Associates of the SoutheastBirmingham, Alabama, United States
Univ of Alabama BirminghamBirmingham, Alabama, United States
Chandler Regional Medical CenterChandler, Arizona, United States
Abrazo Diabetes Care CenterGlendale, Arizona, United States
Central Arkansas Veteran's Healthcare SystemLittle Rock, Arkansas, United States
Cardio Innovation & Resch CtrLong Beach, California, United States
Angel City Research, Inc.Los Angeles, California, United States
St. Joseph Heritage Healthcare_Mission ViejoMission Viejo, California, United States
Adventist Hlth St Helena HospSt. Helena, California, United States
Stanford University Medical CenterStanford, California, United States
Stanford University_StanfordStanford, California, United States

+ 271 more locations — full list on the registry record.

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