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Study identifier: NCT04556773 Synced from ClinicalTrials.gov · August 03, 2026
● Active Not Recruiting

A Phase 1b Study of T-DXd Combinations in HER2-low Advanced or Metastatic Breast Cancer

Condition: Metastatic Breast Cancer  ·  Sponsor: AstraZeneca

PhasePhase 1
Planned participants138
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

DESTINY-Breast 08 will investigate the safety, tolerability, PK and preliminary anti-tumour activity of T-DXd in combination with other therapies in patients with Metastatic HER2-low Advanced or Metastatic Breast Cancer

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (37)

Research SiteCommack, New York, United States
Research SiteHarrison, New York, United States
Research SiteNew York, New York, United States
Research SiteNew York, New York, United States
Research SiteUniondale, New York, United States
Research SiteChapel Hill, North Carolina, United States
Research SiteChattanooga, Tennessee, United States
Research SiteGermantown, Tennessee, United States
Research SiteFort Worth, Texas, United States
Research SiteMelbourne, Australia
Research SiteWestmead, Australia
Research SiteEdegem, Belgium

+ 25 more locations — full list on the registry record.

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