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Study identifier: NCT04544436 Synced from ClinicalTrials.gov · August 02, 2026
● Active Not Recruiting

A Study to Evaluate the Efficacy, Safety and Pharmacokinetics (PK) of a Higher Dose of Ocrelizumab in Adults With Relapsing Multiple Sclerosis (RMS)

Condition: Multiple Sclerosis  ·  Sponsor: Hoffmann-La Roche

PhasePhase 3
Planned participants864
Who can joinAll sexes, 18 Years to 55 Years
Healthy volunteersNo

About this study

This is a randomized, double-blind, controlled, parallel group, multicenter study to evaluate efficacy, safety and PK of a higher dose of ocrelizumab per intravenous (IV) infusion every 24 weeks (Q24W) in participants with RMS, in comparison to the approved 600 milligrams (mg) dose of ocrelizumab.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (120)

North Central Neurology AssociatesCullman, Alabama, United States
Alabama Neurology AssociatesHomewood, Alabama, United States
21st Century NeurologyPhoenix, Arizona, United States
Profound Research, LLCCarlsbad, California, United States
Stanford University Medical CenterStanford, California, United States
Advanced Neurology of Colorado, LLCFort Collins, Colorado, United States
Neurology Associates, PAMaitland, Florida, United States
University of South FloridaTampa, Florida, United States
American Health Network Institute, LLCAvon, Indiana, United States
University of Kansas Medical CenterKansas City, Kansas, United States
The NeuroMedical Clinic of Central LouisianaAlexandria, Louisiana, United States
Maine Medical CenterScarborough, Maine, United States

+ 108 more locations — full list on the registry record.

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