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Study identifier: NCT04474470 Synced from ClinicalTrials.gov · July 30, 2026
● Completed

A Study to Evaluate NT219 Alone and in Combination with ERBITUX® (Cetuximab) in Adults with Advanced Solid Tumors and Head and Neck Cancer

Condition: Solid Tumor, Adult · Squamous Cell Carcinoma of Head and Neck · Colorectal Adenocarcinoma  ·  Sponsor: TyrNovo Ltd.

PhasePhase 1/Phase 2
Planned participants52
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a phase 1/2, multi-center study with an open-label, dose escalation phase followed by a single-arm expansion phase to assess the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of NT219 alone and in combination with ERBITUX® (cetuximab) in adults with recurrent and/or metastatic solid tumors.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (10)

California Cancer Associates for Research and ExcellenceEncinitas, California, United States
The Angeles Clinic and Research InstituteLos Angeles, California, United States
UCSD Moores Cancer CenterSan Diego, California, United States
MedStar Georgetown University HospitalWashington D.C., District of Columbia, United States
The University of Chicago and Biological SciencesChicago, Illinois, United States
Ochsner Clinic FoundationNew Orleans, Louisiana, United States
Stephenson Cancer CenterOklahoma City, Oklahoma, United States
Hadassah University Medical CenterJerusalem, Israel
Rabin Medical CenterPetah Tikva, Israel
Sourasky Medical CenterTel Aviv, Israel

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Source record: clinicaltrials.gov/study/NCT04474470