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Study identifier: NCT04471844 Synced from ClinicalTrials.gov · August 05, 2026
● Completed

Pivotal, Randomized, Open-label Study of Optune® (Tumor Treating Fields) Concomitant With RT & TMZ for the Treatment of Newly Diagnosed GBM

Condition: Glioblastoma Multiforme  ·  Sponsor: NovoCure Ltd.

PhaseNA
Planned participants981
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

To test the effectiveness and safety of Optune® given concomitantly with radiation therapy (RT) and temozolomide (TMZ) in newly diagnosed GBM patients, compared to radiation therapy and temozolomide alone. In both arms, Optune® and maintenance temozolomide are continued following radiation therapy.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (133)

Grandview Cancer CenterBirmingham, Alabama, United States
Banner MD Anderson Cancer CenterGilbert, Arizona, United States
Mayo Clinic- ArizonaPhoenix, Arizona, United States
University of Arizona Cancer CenterTucson, Arizona, United States
Highlands Oncology GroupFayetteville, Arkansas, United States
Providence St. Joseph Medical Center and The Roy and Patricia Disney Family Cancer CenterBurbank, California, United States
City of Hope National Medical CenterDuarte, California, United States
TRIO - St. Jude Heritage Healthcare/St. Jude Medical CenterFullerton, California, United States
University of California at San Diego - Moores Cancer CenterLa Jolla, California, United States
Norris Comprehensive Cancer Center at USCLos Angeles, California, United States
Cedars - Sinai Medical CenterLos Angeles, California, United States
Hoag Memorial Hospital - Hoag Cancer CenterNewport Beach, California, United States

+ 121 more locations — full list on the registry record.

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