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Study identifier: NCT04404283 Synced from ClinicalTrials.gov · August 04, 2026
● Active Not Recruiting

Brentuximab Vedotin Plus Lenalidomide and Rituximab for the Treatment of Relapsed/Refractory DLBCL

Condition: Diffuse Large B-cell Lymphoma  ·  Sponsor: Seagen, a wholly owned subsidiary of Pfizer

PhasePhase 3
Planned participants239
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Participants in this study will have diffuse large B-cell lymphoma (DLBCL) that has come back or not gotten better with treatment. The trial will study whether brentuximab vedotin plus two drugs works better to treat this type of cancer than the two drugs alone. Participants will be randomly assigned to get either brentuximab vedotin or placebo. The placebo will look like brentuximab vedotin, but has no medicine in it. Since the study is "blinded," participants and their doctors will not know whether a participant gets brentuximab vedotin or placebo. All participants in the study will get rituximab and lenalidomide. These are drugs that can be used to treat DLBCL.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (143)

Central Alabama ResearchBirmingham, Alabama, United States
University of California Davis Comprehensive Cancer CenterSacramento, California, United States
University of California Davis Medical CenterSacramento, California, United States
Florida Cancer SpecialistsBonita Springs, Florida, United States
Florida Cancer SpecialistsBradenton, Florida, United States
Florida Cancer SpecialistsCape Coral, Florida, United States
Florida Cancer SpecialistsDaytona Beach, Florida, United States
Florida Cancer SpecialistsFort Myers, Florida, United States
Florida Cancer SpecialistsFort Myers, Florida, United States
Florida Cancer SpecialistsNaples, Florida, United States
Florida Cancer SpecialistsPort Charlotte, Florida, United States
Florida Cancer SpecialistsSarasota, Florida, United States

+ 131 more locations — full list on the registry record.

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