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Study identifier: NCT04337177 Synced from ClinicalTrials.gov · August 02, 2026
● Active Not Recruiting

Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumors

Condition: Solid Tumors · Neuroblastoma · Rhabdomyosarcoma  ·  Sponsor: Valent Technologies, LLC

PhasePhase 1
Planned participants20
Who can joinAll sexes, 1 Year to 30 Years
Healthy volunteersNo

About this study

A pilot pharmacokinetic trial to determine the safety and efficacy of a flavored, orally administered irinotecan VAL-413 (Orotecan®) given with temozolomide for treatment of recurrent pediatric solid tumors including but not limited to neuroblastoma, rhabdomyosarcoma, Ewing sarcoma, hepatoblastoma and medulloblastoma

This description comes directly from the study's public registry record.

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No contact information is available for this study as per the public registry record.

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Locations (11)

Phoenix Children's HospitalPhoenix, Arizona, United States
UCSF, Mission Bay - Benioff Children's HospitalSan Francisco, California, United States
Children's National Research Institute - Children's National HospitalWashington D.C., District of Columbia, United States
Children's Healthcare of Atlanta - Arthur M. Blank HospitalAtlanta, Georgia, United States
Indiana University School of Medicine, Riley Hospital for ChildrenIndianapolis, Indiana, United States
Washington University - St. LouisSt Louis, Missouri, United States
University of North Carolina at Chapel Hill - North Carolina Cancer HospitalChapel Hill, North Carolina, United States
Atrium Health Levine Children's Hospital - Carolinas Medical CenterCharlotte, North Carolina, United States
Duke University Children's Hospital and Health CenterDurham, North Carolina, United States
Cincinnati Children's Hospital Medical CenterCincinnati, Ohio, United States
Sarah Cannon Research Institute, Pediatric Hematology & OncologyNashville, Tennessee, United States

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