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Study identifier: NCT04284436 Synced from ClinicalTrials.gov · August 03, 2026
● Active Not Recruiting

Study in Parkinson Disease of Exercise

Condition: Parkinson Disease  ·  Sponsor: Northwestern University

PhaseNA
Planned participants370
Who can joinAll sexes, 40 Years to 80 Years
Healthy volunteersNo

About this study

This study is a Phase 3 multi-site, randomized, evaluator-masked, study of endurance treadmill exercise on changes in the Movement Disorder Society-Unified Parkinson Disease Rating Scale (MDS-UPDRS) Part III score at 12 months among persons with early stage Parkinson disease. 370 participants will be randomly assigned to 2 groups: 1)60-65% HRmax or 2)80-85% HRmax 4 times per week. The primary objective is to test whether the progression of the signs of Parkinson's disease is attenuated at 12 months in among persons who have not initiated medication for Parkinson Disease (PD) when they perform high-intensity endurance treadmill exercise.

This description comes directly from the study's public registry record.

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No contact information is available for this study as per the public registry record.

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Locations (25)

University of Alabama at BirminghamBirmingham, Alabama, United States
University of California, San FranciscoSan Francisco, California, United States
University of Colorado, DenverAurora, Colorado, United States
University of FloridaGainesville, Florida, United States
Morehouse School of MedicineAtlanta, Georgia, United States
Emory UniversityAtlanta, Georgia, United States
Northwestern UniversityChicago, Illinois, United States
Rush University Medical CenterChicago, Illinois, United States
Iowa State UniversityAmes, Iowa, United States
Louisiana State UniversityBaton Rouge, Louisiana, United States
Boston University (Charles River Campus)Boston, Massachusetts, United States
University of MichiganAnn Arbor, Michigan, United States

+ 13 more locations — full list on the registry record.

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