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Study identifier: NCT04196868 Synced from ClinicalTrials.gov · August 04, 2026
● Completed

Methotrexate and Metformin in Rheumatoid Arthritis Patients

Condition: Arthritis, Rheumatoid  ·  Sponsor: University Hospital, Bordeaux

PhasePhase 2
Planned participants128
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Methotrexate (MTX) is the anchor drug for patients with rheumatoid arthritis (RA). Despite its marked efficacy and acceptable side effect profile, about 1/3 of patients failed to reach RA remission. Metformin is the first-line therapy for type 2 diabetes. Its antioxidative and anti-inflammatory properties make it a good candidate for the treatment of inflammatory diseases such as rheumatoid arthritis.

This description comes directly from the study's public registry record.

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No contact information is available for this study as per the public registry record.

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Locations (12)

CH de la Côte Basque - service de rhumatologieBayonne, France
CHU de Bordeaux - service de rhumatologieBordeaux, France
CHU de Brest - service de rhumatologieBrest, France
CH de Cahors - service de rhumatologieCahors, France
Clinique de l'Infirmerie protestante de Lyon - service de rhumatologieCaluire-et-Cuire, France
CHD de Vendée - service de rhumatologieLa Roche-sur-Yon, France
CH du Mans - service de rhumatologieLe Mans, France
CH de Libourne - service de rhumatologieLibourne, France
CHU de Montpellier - service de rhumatologieMontpellier, France
CHR Orléans la Source - service de rhumatologieOrléans, France
CH de Pau - service de rhumatologiePau, France
CHU de Toulouse - service de rhumatolgieToulouse, France

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