Condition: Metastatic Cholangiocarcinoma · Metastatic Hepatocellular Carcinoma · Stage III Hepatocellular Carcinoma AJCC v8 · Sponsor: National Cancer Institute (NCI)
This phase II trial studies how well pevonedistat alone or in combination with chemotherapy (paclitaxel and carboplatin) works in treating patients with bile duct cancer of the liver. Pevonedistat may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Chemotherapy drugs, such as paclitaxel and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. This study may help the study doctors find out how well pevonedistat shrinks bile duct cancer of the liver when given alone and when in combination with paclitaxel and carboplatin.
This description comes directly from the study's public registry record.
No contact information is available for this study as per the public registry record.
Always discuss trial participation with your own doctor first.
| Anchorage Associates in Radiation Medicine | Anchorage, Alaska, United States | — |
| Anchorage Radiation Therapy Center | Anchorage, Alaska, United States | — |
| Alaska Breast Care and Surgery LLC | Anchorage, Alaska, United States | — |
| Alaska Oncology and Hematology LLC | Anchorage, Alaska, United States | — |
| Alaska Women's Cancer Care | Anchorage, Alaska, United States | — |
| Anchorage Oncology Centre | Anchorage, Alaska, United States | — |
| Katmai Oncology Group | Anchorage, Alaska, United States | — |
| Providence Alaska Medical Center | Anchorage, Alaska, United States | — |
| Kingman Regional Medical Center | Kingman, Arizona, United States | — |
| Cancer Center at Saint Joseph's | Phoenix, Arizona, United States | — |
| CHI Saint Vincent Cancer Center Hot Springs | Hot Springs, Arkansas, United States | — |
| Mission Hope Medical Oncology - Arroyo Grande | Arroyo Grande, California, United States | — |
+ 407 more locations — full list on the registry record.
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