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Study identifier: NCT04173273 Synced from ClinicalTrials.gov · August 05, 2026
● Terminated

A Study Evaluating the Efficacy and Safety of Oral Etrasimod in the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease

Condition: Crohn's Disease  ·  Sponsor: Pfizer

PhasePhase 2/Phase 3
Planned participants379
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

This is a Phase 2/3 study that comprises 5 substudies designed to evaluate the efficacy, safety, and tolerability of oral etrasimod as therapy in adult participants with moderately to severely active Crohn's disease (CD) who are refractory or intolerant to at least 1 of the current therapies for CD (ie, corticosteroids, immunosuppressants, or biologics). The overall duration of this study is up to 282 weeks, inclusive of the Screening Period, Treatment Period of up to 274 weeks (Induction, Extension or Maintenance, and Long-term Extension Periods), and the 4-Week Follow-Up Period for safety assessment.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (510)

Center for Digestive Health (Endoscopy Location)Dothan, Alabama, United States
Digestive Health SpecialistsDothan, Alabama, United States
Dothan Eyecare-Dr. Brent McKinley (OCT Location)Dothan, Alabama, United States
Pulmonary Associates (PFT Location)Dothan, Alabama, United States
Flowers Hospital (Imaging Location)Dothan, Alabama, United States
Digestive Health Specialists (Satellite Clinic Location)Mobile, Alabama, United States
Premier Medical Group East (Opthalmology & Optometry Facility)Mobile, Alabama, United States
Pulmonary Associates (Chest X-Ray & PFT Facility)Mobile, Alabama, United States
Surgicare of Mobile (Endoscopy & Biopsy Facility)Mobile, Alabama, United States
Arizona Retina Institute/ Phoenix Retina Associates(OCT)Peoria, Arizona, United States
SimonMed Imaging (Imaging)Peoria, Arizona, United States
Sun City Endoscopy Center (Endoscopy)Sun City, Arizona, United States

+ 498 more locations — full list on the registry record.

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